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Thiamine Hydrochloride Vitamin B1 Powder
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Description
Thiamine Hydrochloride
Other Names: Thiamine HCl, Aneurine hydrochloride, Vitamin B1 hydrochloride
CAS Number: 67-03-8
Sum Formula: C₁₂H₁₈Cl₂N₄OS
Molar Mass: 337.30 g/mol
Appearance: White to off-white crystalline powder
Thiamine hydrochloride is the hydrochloride salt form of thiamine (vitamin B1), a sulfur-containing, water-soluble vitamin. It is a chemically stable form of thiamine used in technical, biochemical, and industrial formulations where water solubility and stability are essential.
Chemical and Physical Properties
Density: ~1.6 g/cm³ (estimated)
Melting Point: 250–252°C (decomposes)
Boiling Point: Not applicable (decomposes)
Solubility in Water: Freely soluble (>100 g/L at 20°C)
Solubility in Other Solvents: Slightly soluble in ethanol; practically insoluble in ether and chloroform
Odor: Odorless
Applications
Organic Synthesis: Used as a building block in the synthesis of thiazole and pyrimidine derivatives.
Biochemical Research: Applied in enzymology and studies of thiamine-dependent biochemical pathways.
Chemical Manufacturing: Precursor for thiamine analogues and derivatives in technical formulations.
Material Science: Investigated for incorporation into water-soluble functional polymers and bioactive materials.
Analytical Chemistry: Employed as a standard or reactant in vitamin determination assays.
Safety
Signal Word: Warning
P264+P265, P280, P305+P351+P338, and P337+P317
Handling and Storage
Storage Conditions: Store in a tightly sealed container in a cool, dry, and well-ventilated place. Protect from moisture, light, and strong oxidizing agents.
Handling Precautions: Avoid creating dust and direct contact with eyes or mucous membranes. Use standard laboratory or industrial safety equipment and practices.