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Pure Biotin Powder ( vitamin B7 )
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Description
Biotin Pure Powder
Other Names: 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid, Vitamin B7
CAS Number: 58-85-5
Sum Formula: C₁₀H₁₆N₂O₃S
Molar Mass: 244.31 g/mol
Appearance: White to off-white crystalline powder
Biotin is a water-soluble B-complex vitamin composed of a ureido ring fused with a tetrahydrothiophene ring and a valeric acid substituent. It plays a vital role as a coenzyme in carboxylation reactions and is used in synthetic chemistry, biochemical research, and materials science involving bioconjugation and surface modification.
Chemical and Physical Properties
Density: ~1.3 g/cm³ (estimated)
Melting Point: 232–235°C (decomposes)
Boiling Point: Not applicable (decomposes)
Solubility in Water: Slightly soluble (~22 mg/L at 25°C)
Solubility in Other Solvents: Soluble in dilute alkali; sparingly soluble in ethanol; practically insoluble in ether and chloroform
Odor: Odorless
Applications
Organic Synthesis: Used in the preparation of biotinylated molecules and conjugates.
Biochemical Research: Employed in studies of enzyme-coenzyme systems, particularly carboxylases.
Surface Chemistry: Applied in biotin-streptavidin affinity systems for biomaterials and sensor technologies.
Analytical Chemistry: Used in assays involving biotin-avidin interactions and biomolecule labeling.
Polymer Science: Investigated for functionalization of polymers to introduce specific binding sites.
Safety
This chemical does not meet GHS hazard criteria for 99.6% (265 of 266) of all reports.
Handling and Storage
Storage Conditions: Store in a tightly sealed container in a cool, dry, and dark place. Protect from light, moisture, and strong oxidizing agents.
Handling Precautions: Avoid dust formation and direct contact with eyes or mucous membranes. Use appropriate PPE and observe standard chemical safety protocols.