Lidocaine ( Lignocaine ) | Pure

Lidocaine
Other Names: 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide

CAS Number: 137-58-6
Sum Formula: C₁₄H₂₂N₂O
Molar Mass: 234.34 g/mol
Appearance: White crystalline powder

Lidocaine is an organic compound classified as an amide-type local anesthetic. It is widely used in chemical, industrial, and research applications where local anesthetic or antiarrhythmic properties are required. Lidocaine exhibits high membrane penetration and rapid onset of action.

Chemical and Physical Properties
Density: ~1.03 g/cm³ (at 20°C, estimated for the liquid form)
Melting Point: 66–69°C
Boiling Point: 350°C (decomposes)
Solubility in Water: Slightly soluble (1.4 g/L at 25°C)
Solubility in Other Solvents: Soluble in ethanol, chloroform, and acetone
Odor: Odorless
Taste: Slightly bitter

Applications
Chemical Synthesis: Used as an intermediate for the preparation of related amide compounds.
Industrial Research: Applied in the development of drug delivery systems and studies of membrane permeability.
Surface Science: Studied for its interactions with lipid membranes and protein systems.
Specialty Applications: Used in chemical studies involving ion channels and electrophysiological processes.

Key Properties

• Rapid Action: Fast penetration into lipid layers, effective for local applications.

• Stability: Stable under normal storage conditions, resistant to hydrolysis under neutral pH.

• Versatile Solubility: Compatible with polar organic solvents for formulation flexibility.

Safety

Signal Word: Warning

Handling and Storage
Storage Conditions:

• Store in a tightly closed container in a cool, dry, and well-ventilated place.

• Protect from moisture, strong oxidizers, and high heat.

• Recommended storage temperature: below 25°C.

Handling Precautions:

• Avoid creating dust.

• Use appropriate personal protective equipment (PPE) including gloves, goggles, and dust mask during handling.