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Antipyrine ( Fenazone ) [CAS: 60-80-0] - 250g
![Antipyrine ( Fenazone ) [CAS: 60-80-0] - 250g](/userdata/public/gfx/14965/69ac372e4d7b9ea0e1d739fe0e9f438b.jpg)
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 [CAS: 60-80-0] - 250g "Pin It")
Description
Antipyrine (Phenazone)
Other Names: 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
CAS Number: 60-80-0
Sum Formula: C₁₁H₁₂N₂O
Molar Mass: 188.23 g/mol
Appearance: White crystalline powder
Antipyrine (also known as phenazone) is an organic compound belonging to the pyrazolone class. It is historically significant as one of the first synthetic fever-reducing agents and remains relevant in chemical research, analytical chemistry, and organic synthesis.
Chemical and Physical Properties
Density: ~1.19 g/cm³ (estimated)
Melting Point: 113–116°C
Boiling Point: Decomposes before boiling
Solubility in Water: Freely soluble
Solubility in Other Solvents: Soluble in alcohol, chloroform, and acetone
Odor: Odorless
Applications
Analytical Chemistry: Used as a standard in the calibration of spectrophotometric methods and as a reagent in colorimetric assays.
Organic Synthesis: Applied as an intermediate in the preparation of other pyrazolone derivatives and related compounds.
Chemical Research: Studied for its redox behavior and ability to form stable complexes with metals.
Material Science: Explored for potential roles in coordination chemistry and development of functional materials.
Safety
Signal Word: Warning
H302 (99.5%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (54.9%): Causes skin irritation [Warning Skin corrosion/irritation]
H317 (46.2%): May cause an allergic skin reaction [Warning Sensitization, Skin]
H319 (54.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (54.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Handling and Storage
Storage Conditions: Store in a tightly closed container in a cool, dry, and well-ventilated area. Protect from strong oxidizing agents and moisture.
Handling Precautions: Avoid dust formation and exposure to skin or eyes. Use appropriate PPE and standard laboratory safety practices.