1-(3-FLUOROPHENYL)-2-NITROPROPENE

1-(3-Fluorophenyl)-2-nitropropene
Other Names:

• (E)-1-(3-Fluorophenyl)-2-nitropropene

• 3-Fluorophenyl-2-nitropropene

• 1-(m-Fluorophenyl)-2-nitropropene

CAS Number: 1737-01-5
Sum Formula: C₉H₈FNO₂
Molar Mass: 181.16 g/mol
Appearance: Yellow to orange crystalline solid or powder

1-(3-Fluorophenyl)-2-nitropropene is an aromatic nitroalkene bearing a fluorine atom in the meta position of the phenyl ring. It is primarily used in research and organic synthesis, particularly in reactions involving conjugated alkenes or fluorinated intermediates.

Chemical and Physical Properties
Density: Approx. 1.25 g/cm³ (estimated)
Melting Point: ~58–62°C
Boiling Point: Decomposes before boiling
Solubility in Water: Practically insoluble
Solubility in Other Solvents: Soluble in acetone, ethanol, methanol, and DCM
Odor: Mild aromatic odor

Applications
Organic Synthesis: Used as a building block for fluorinated phenyl compounds and in electrophilic/nucleophilic addition reactions.
Chemical Research: Studied for its electron-withdrawing nitro group and its conjugated reactivity.
Intermediate: Precursor for further functionalized aromatic and heterocyclic derivatives.

Safety
Signal Word: Warning

Hazard Statements:
H302: Harmful if swallowed
H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
H411: Toxic to aquatic life with long lasting effects

Precautionary Statements – Prevention:
P261: Avoid breathing dust or vapors
P264: Wash hands thoroughly after handling
P273: Avoid release to the environment
P280: Wear protective gloves and eye protection

Precautionary Statements – Response:
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell
P302+P352: IF ON SKIN: Wash with plenty of water
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
P337+P313: If eye irritation persists: Get medical advice/attention

Handling and Storage
Storage Conditions: Store in a tightly closed container in a cool, dry, and well-ventilated area. Keep away from light, moisture, and incompatible substances such as strong oxidizers.
Handling Precautions: Avoid formation of dust and direct contact with skin or eyes. Use appropriate personal protective equipment and handle under a fume hood if possible.