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Tryptamine Free Base [ 2-(1H-Indol-3-yl)ethan-1-amine ] CAS 61-54-1 >99% - 1000g

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Description

Tryptamine Free Base
Other Names: 2-(1H-Indol-3-yl)ethan-1-amine
CAS Number: 61-54-1
Sum Formula: C₁₀H₁₂N₂
Molar Mass: 160.22 g/mol
Appearance: White to off-white crystalline powder

Tryptamine is a naturally occurring monoamine alkaloid and trace amine derived from the amino acid tryptophan. It is structurally characterized by an indole ring and an ethylamine side chain. This compound serves as a biochemical precursor in various metabolic pathways and has significance in organic synthesis and pharmacological research.


Chemical and Physical Properties

  • Density: ~1.2 g/cm³

  • Melting Point: 113–118°C

  • Boiling Point: Decomposes before boiling

  • Solubility in Water: Slightly soluble

  • Solubility in Organic Solvents: Soluble in ethanol, chloroform, and DMSO

  • Odor: Odorless

  • Stability: Sensitive to oxidation; store under inert atmosphere


Applications

  • Chemical Synthesis: Used as a building block in the synthesis of tryptamine derivatives, including many indole-based compounds.

  • Pharmacological Research: Investigated for its role in neurotransmission and as a precursor to bioactive compounds.

  • Biochemistry: Serves as a model compound for studying metabolic pathways involving tryptophan-derived alkaloids.

  • Organic Chemistry: Useful for producing functionalized indoles and exploring reaction mechanisms involving amines.


Safety

Signal Word: Warning

GHS Hazard Statements

H315 (96.2%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (96.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H335 (92.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statement Codes

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501


Handling and Storage

  • Storage Conditions: Store in a cool, dry place under inert gas. Keep tightly sealed and protected from light and moisture.

  • Handling Precautions: Avoid dust formation and contact with eyes or skin. Use suitable protective gear and ensure adequate ventilation.

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