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Syringaldehyde ( 4-Hydroxy-3,5-dimethoxybenzaldehyde )
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Description
Syringaldehyde
Other Names: 4-Hydroxy-3,5-dimethoxybenzaldehyde
CAS Number: 134-96-3
Molecular Formula: C₉H₁₀O₄
Molar Mass: 182.17 g/mol
Appearance: White to pale yellow crystalline powder
Syringaldehyde is an aromatic aldehyde derived from lignin degradation. It contains both methoxy and hydroxyl substituents on a benzaldehyde core, making it useful in organic synthesis and research. It is commonly used as an intermediate in the production of fine chemicals, fragrances, and as a reagent in analytical and biochemical applications.
Chemical and Physical Properties
Density: ~1.24 g/cm³
Melting Point: 110–113 °C
Boiling Point: 297 °C (decomposes)
Solubility in Water: Slightly soluble
Solubility in Other Solvents: Soluble in ethanol, methanol, ether
Odor: Characteristic, faint vanilla-like
Applications
Organic Synthesis: Intermediate in the synthesis of pharmaceuticals, fragrances, and agrochemicals.
Analytical Chemistry: Employed in biochemical and structural studies of lignin and phenolic compounds.
Research: Used in studies related to natural product synthesis and oxidation reactions.
Safety
Signal Word: Warning
H302 (97.6%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (> 99.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Handling and Storage
Store in a tightly sealed container in a cool, dry, and well-ventilated area. Avoid exposure to heat, light, and moisture. Use appropriate personal protective equipment when handling.