Serine Powder

Serine
Other Names: L-Serine, (S)-2-Amino-3-hydroxypropanoic acid, H-Ser-OH

CAS Number: 56-45-1
Sum Formula: C₃H₇NO₃
Molar Mass: 105.09 g/mol
Appearance: White crystalline powder

L-Serine is a naturally occurring α-amino acid containing a primary alcohol functional group on its side chain. As one of the 20 standard amino acids, it plays a key role in biosynthetic pathways and is frequently used in chemical synthesis, protein research, and materials development.

Chemical and Physical Properties
Density: ~1.6 g/cm³ (estimated)
Melting Point: ~228°C (with decomposition)
Boiling Point: Not applicable (decomposes)
Solubility in Water: Very soluble (~43 g/100 mL at 20°C)
Solubility in Other Solvents: Slightly soluble in ethanol; insoluble in ether and chloroform
Odor: Odorless

Applications
Peptide Synthesis: Used as a building block for serine-containing peptides and proteins.
Chemical Modification: Serves as a precursor for serine-derived ligands and functionalized molecules.
Biochemistry and Enzymology: Commonly employed in enzyme studies and protein folding investigations.
Polymer and Materials Science: Studied in bio-based polymers and hydrogels due to its hydroxyl functionality.
Analytical Chemistry: Applied in amino acid profiling, chromatography, and calibration standards.

Safety

This chemical does not meet GHS hazard criteria for 94% (236 of 251) of all reports.

Handling and Storage
Storage Conditions: Store in a tightly sealed container in a cool, dry, and well-ventilated environment. Protect from moisture and light.
Handling Precautions: Avoid dust formation and contact with skin or eyes. Use proper PPE and follow general laboratory safety practices.