Niacin - Nicotinic Acid - Vitamin PP - Vitamin B3 - Bionic ( Pyridine-3-carboxylic acid ) - 1000g

Niacin (Nicotinic Acid, Vitamin B3, Vitamin PP, Pyridine-3-carboxylic Acid)
Chemical Formula: C₆H₅NO₂
Molar Mass: 123.11 g/mol
CAS Number: 59-67-6
Appearance: White to off-white crystalline powder
Synonyms: Pyridine-3-carboxylic acid, Bionic acid

Niacin, also known as nicotinic acid or pyridine-3-carboxylic acid, is a monocarboxylic acid derived from pyridine. It is a chemically stable, water-soluble compound used in chemical synthesis, laboratory research, and various industrial applications involving pyridine derivatives.

Chemical and Physical Properties

• Density: ~1.47 g/cm³

• Melting Point: 236–238°C

• Boiling Point: Decomposes before boiling

• Solubility in Water: ~15 g/L at 25°C

• Solubility in Other Solvents: Soluble in ethanol, slightly soluble in ether

• Odor: Odorless

• pKa: ~4.8 (carboxylic group)

Applications

Organic Synthesis

• Used as an intermediate in the production of pyridine-based compounds and heterocyclic derivatives.

Analytical Chemistry

• Employed as a reference substance and reagent in pH-dependent reactions and titration procedures.

Chemical Processing

• Acts as a building block for modified carboxylic acids and amide derivatives in industrial chemistry.

Metal Surface Treatment

• Sometimes explored in metal chelation studies or modification of electrode surfaces.

Safety

Signal Word: Warning

Hazard Statements:

• H319: Causes serious eye irritation

• H335: May cause respiratory irritation

• EUH066: Repeated exposure may cause skin dryness or cracking

Precautionary Statements:

• P261: Avoid breathing dust

• P264: Wash hands thoroughly after handling

• P271: Use only outdoors or in a well-ventilated area

• P280: Wear protective gloves and eye protection

• P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing

• P337+P313: If eye irritation persists: Get medical advice/attention

Handling and Storage

• Storage Conditions: Store in a tightly sealed container in a dry, cool, and well-ventilated area.

• Handling Precautions: Avoid generation of dust. Use appropriate PPE including gloves, safety goggles, and dust mask during handling.

• Compatibility: Avoid contact with strong oxidizing agents.

Environmental Considerations

Niacin is considered low hazard to the environment, but large quantities should not be released into wastewater or soil. Follow local regulations for disposal.