N-Acetylglucosamine
Other Names: β-D-(Acetylamino)-2-deoxy-glucopyranose, N-Acetyl-D-glucosamine, GlcNAc, NAG

CAS Number: 7512-17-6
Sum Formula: C₈H₁₅NO₆
Molar Mass: 221.21 g/mol
Appearance: White to off-white crystalline powder

N-Acetylglucosamine (GlcNAc) is a monosaccharide derivative of glucose, containing an acetylated amino group at the C-2 position. It is a fundamental building block in the biosynthesis of glycoproteins, glycolipids, and polysaccharides and is widely studied for its role in biochemistry, materials science, and synthetic chemistry.

Chemical and Physical Properties
Density: ~1.56 g/cm³ (estimated)
Melting Point: ~190°C (decomposes)
Boiling Point: Not applicable (decomposes)
Solubility in Water: Freely soluble
Solubility in Other Solvents: Slightly soluble in ethanol; practically insoluble in ether and chloroform
Odor: Odorless

Applications
Polymer and Material Science: Used in the synthesis of biodegradable polymers and hydrogels.
Glycochemistry: Applied as a starting material for the preparation of oligosaccharides and glycosylated compounds.
Biochemical Research: Studied for its involvement in cell signaling, protein glycosylation, and chitin biosynthesis.
Surface Chemistry: Employed in the functionalization of materials for biological compatibility and targeting.
Analytical Chemistry: Used as a standard or reactant in assays involving carbohydrate analysis and glycan profiling.

Safety

This chemical does not meet GHS hazard criteria for 100% (50 of 50) of all reports.

Handling and Storage
Storage Conditions: Store in a tightly sealed container in a cool, dry, and well-ventilated environment. Protect from moisture and strong oxidizing agents.
Handling Precautions: Avoid creating dust and direct exposure to eyes or skin. Use standard PPE and good laboratory practices.