Ethyl Glycinate Hydrochloride | 2-Aminoacetic acid ethyl ester

Ethyl Glycinate Hydrochloride
Other Names: Glycine ethyl ester hydrochloride, 2-Aminoacetic acid ethyl ester hydrochloride
CAS Number: 623-33-6
Sum Formula: C₄H₁₀ClNO₂
Molar Mass: 139.58 g/mol
Appearance: White to off-white crystalline powder

Ethyl glycinate hydrochloride is the hydrochloride salt of the ethyl ester of glycine. It is used as an intermediate in organic synthesis, particularly in the preparation of peptides, amino acid derivatives, and pharmaceutical research compounds. Its crystalline nature and high solubility in water and alcohols make it a versatile reagent in laboratory-scale chemistry.

Chemical and Physical Properties
Density: Not determined (solid)
Melting Point: 146–150°C (with decomposition)
Boiling Point: Not applicable (decomposes before boiling)
Solubility in Water: Highly soluble
Solubility in Organic Solvents: Soluble in ethanol, methanol
Odor: Odorless or faint
Stability: Stable under recommended storage conditions

Applications
Intermediate in peptide synthesis and amino acid derivatization
Used in the production of specialty organic compounds
Laboratory reagent for synthesis of amide and ester derivatives
Applied in research on amino acid ester chemistry

Safety

Signal Word: Warning

First Aid Measures
Eye Contact: Rinse immediately with water for several minutes. Seek medical attention if irritation occurs
Skin Contact: Wash thoroughly with soap and water. Remove contaminated clothing
Inhalation: Move to fresh air. Seek medical help if symptoms develop
Ingestion: Rinse mouth with water. Seek medical attention if discomfort occurs

Handling and Storage
Store in a tightly sealed container in a cool, dry place
Protect from moisture and direct sunlight
Use appropriate PPE when handling to avoid contact with skin, eyes, and clothing