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Antipyrine ( Phenazone - Antipyrin - Phenazon ) [CAS: 60-80-0] - 50g

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Description

Antipyrine
Other Names: Phenazone, Antipyrin, Phenazon
CAS Number: 60-80-0
Sum Formula: C₁₁H₁₂N₂O
Molar Mass: 188.23 g/mol
Appearance: White to off-white crystalline powder

Antipyrine is a synthetic organic compound from the pyrazolone class. It has historically been used as an analgesic and antipyretic agent, and today is primarily applied in analytical chemistry, organic synthesis, and industrial research.


Chemical and Physical Properties

  • Density: ~1.2 g/cm³

  • Melting Point: 110–113 °C

  • Boiling Point: Decomposes before boiling

  • Solubility in Water: Slightly soluble

  • Solubility in Other Solvents: Soluble in ethanol, acetone, chloroform

  • Odor: Odorless

  • Stability: Stable under normal conditions; sensitive to light and heat


Applications

  • Analytical Chemistry: Used as a reagent in chemical testing and photometric assays.

  • Organic Synthesis: Acts as an intermediate in the preparation of various heterocyclic compounds.

  • Industrial Research: Employed in the development of dye compounds and materials chemistry.

  • Reference Compound: Utilized in laboratory calibrations and method validation due to its defined properties.


Safety

Signal Word: Warning

GHS Hazard Statements

H302 (99.5%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (54.9%): Causes skin irritation [Warning Skin corrosion/irritation]

H317 (46.2%): May cause an allergic skin reaction [Warning Sensitization, Skin]

H319 (54.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H335 (54.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statement Codes

P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501


Handling and Storage

  • Storage Conditions: Keep container tightly closed in a cool, dry, and well-ventilated area. Protect from light and moisture.

  • Handling Precautions: Avoid generating dust. Use personal protective equipment and avoid contact with eyes and skin.

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