5-Bromovanillin

5-Bromovanillin
Other Names:

• 3-Bromo-4-hydroxy-5-methoxybenzaldehyde

• Benzaldehyde, 3-bromo-4-hydroxy-5-methoxy-

• Vanillin, 5-bromo-

CAS Number: 2973-76-4
Sum Formula: C₈H₇BrO₃
Molar Mass: 231.04 g/mol
Appearance: Light beige to off-white crystalline solid

5-Bromovanillin is a brominated aromatic aldehyde structurally related to vanillin. It contains methoxy, hydroxyl, and formyl groups substituted on a brominated benzene ring. It is primarily used as a reagent and intermediate in organic synthesis, especially in the preparation of more complex heterocyclic and aromatic compounds.

Chemical and Physical Properties
Density: Approx. 1.7 g/cm³ (estimated)
Melting Point: 188–191°C
Boiling Point: Decomposes before boiling
Solubility in Water: Slightly soluble
Solubility in Other Solvents: Soluble in ethanol, methanol, acetone, and ether
Odor: Mild aromatic odor

Applications
Organic Synthesis: Intermediate in the preparation of heterocyclic and halogenated aromatic compounds.
Material Chemistry: Used in the synthesis of molecular precursors for advanced materials.
Analytical Chemistry: Sometimes employed as a derivatization agent or aromatic reference standard.
Research: Investigated in studies involving substituted vanillin derivatives and structure–activity relationships.

Safety

Signal Word: Warning

Handling and Storage
Storage Conditions: Store in a tightly closed container in a cool, dry, and well-ventilated place. Protect from light, moisture, and incompatible substances such as strong oxidizing agents.
Handling Precautions: Avoid dust formation and contact with skin or eyes. Use proper laboratory protective equipment and follow good hygiene practices.