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4-fluorobenzaldehyde Fluorobenzaldehyde Pure For Organic Synthesis - 1000ml

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Description

4-Fluorobenzaldehyde

Other Namesp-Fluorobenzaldehyde, para-Fluorobenzaldehyde
Chemical Formula: C₇H₅FO
Molar Mass: 124.11 g/mol
CAS Number: 459-57-4
Purity: ≥99% (analytical or synthesis grade)
Appearance: Colorless to pale yellow liquid
Odor: Characteristic aromatic aldehyde odor

4-Fluorobenzaldehyde is an aromatic fluorinated aldehyde, widely used as a building block in organic synthesis and a precursor in the preparation of fine chemicals, polymers, and functionalized materials. It features both electrophilic aldehyde and fluorinated aromatic functionalities, making it reactive in various substitution, condensation, and coupling reactions.


Chemical and Physical Properties

  • Density: ~1.17 g/cm³ at 20 °C

  • Melting Point: −1 °C

  • Boiling Point: ~174–176 °C

  • Flash Point: 66 °C

  • Solubility in Water: Slightly soluble

  • Solubility in Organic Solvents: Miscible with ethanol, ether, acetone, benzene

  • Reactivity: Sensitive to strong oxidizing agents and bases; undergoes typical aldehyde reactions


Applications

  • Organic Synthesis: Key intermediate in the synthesis of fluorinated compounds, Schiff bases, and aromatic heterocycles.

  • Materials Science: Used in the preparation of functionalized polymers and coatings.

  • Aromatic Substitutions: Suitable for nucleophilic and electrophilic substitution reactions on the fluorinated ring.

  • Ligand and Complex Chemistry: Precursor for custom-designed ligands and coordination compounds.


Safety

Signal Word: ⚠️ Warning

Hazard Statements:

  • H302: Harmful if swallowed

  • H315: Causes skin irritation

  • H319: Causes serious eye irritation

  • H335: May cause respiratory irritation

  • H411: Toxic to aquatic life with long lasting effects

Precautionary Statements:

  • P261: Avoid breathing vapors

  • P280: Wear protective gloves, protective clothing, eye and face protection

  • P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell

  • P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing

  • P273: Avoid release to the environment

  • P501: Dispose of contents/container in accordance with local regulations


Handling and Storage

  • Handling: Use in a fume hood. Avoid inhalation and contact with skin or eyes. Use appropriate personal protective equipment (PPE).

  • Storage: Store in a tightly sealed container in a cool, dry, well-ventilated area. Protect from light, heat, and incompatible materials.


Environmental Considerations

Toxic to aquatic life in higher concentrations. Prevent uncontrolled release to soil, surface water, or drainage systems.

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