Pyridinium Chlorochromate (PCC)

Pyridinium Chlorochromate (PCC)
Other Names: PCC, Pyridinium chlorochromate(VI)
CAS Number: 26299-14-9
Sum Formula: C₅H₆ClCrNO₃
Molar Mass: 215.56 g/mol
Appearance: Orange to reddish crystalline powder

Pyridinium Chlorochromate (PCC) is a well-known oxidizing agent used in organic synthesis. It is particularly valued for the selective oxidation of primary alcohols to aldehydes and secondary alcohols to ketones without over-oxidizing to carboxylic acids. PCC provides controlled reaction conditions and is widely applied in laboratory and fine chemical synthesis.

Chemical and Physical Properties
Density: ~1.7 g/cm³
Melting Point: Decomposes on heating (above 200°C)
Solubility: Slightly soluble in water; soluble in polar organic solvents such as acetonitrile and dichloromethane
Stability: Stable when stored properly; decomposes upon strong heating; incompatible with strong reducing agents and combustible materials

Applications
Oxidizing agent in organic synthesis
Selective oxidation of alcohols to aldehydes or ketones
Applied in laboratory and fine chemical synthesis where mild oxidation is required

Safety

Signal Word: Danger

Hazard Statements

H272 May intensify fire; oxidizer.

H317 May cause an allergic skin reaction.

H350i May cause cancer by inhalation.

H410 Very toxic to aquatic life with long lasting effects.

Precautionary Statements

P202 Do not handle until all safety precautions have been read and understood.

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

P273 Avoid release to the environment.

P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.

P302 + P352 IF ON SKIN: Wash with plenty of water.

P308 + P313 IF exposed or concerned: Get medical advice/ attention.

First Aid Measures
Eye Contact: Rinse immediately with plenty of water for several minutes. Seek immediate medical attention
Skin Contact: Wash with soap and water for at least 15 minutes. Remove contaminated clothing. Seek medical help
Inhalation: Move to fresh air. Administer oxygen if needed. Seek immediate medical attention
Ingestion: Rinse mouth with water. Do not induce vomiting. Seek urgent medical care

Handling and Storage
Store in a tightly closed container in a cool, dry, well-ventilated area
Keep away from heat, sparks, and combustible materials
Avoid dust formation; handle under fume hood
Store separately from reducing agents, strong acids, and organic materials