Melatonin
Other Names: N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide

CAS Number: 73-31-4
Sum Formula: C₁₃H₁₆N₂O₂
Molar Mass: 232.28 g/mol
Appearance: White to off-white crystalline powder

Melatonin is an organic compound belonging to the class of indoleamines, structurally related to serotonin. It is commonly used as a chemical reagent for laboratory research, particularly in studies involving biological rhythms, oxidative stress, and receptor binding.

Chemical and Physical Properties
Density: ~1.17 g/cm³ (estimated)
Melting Point: 116–118°C
Boiling Point: Decomposes before boiling
Solubility in Water: Slightly soluble (about 2.5 mg/mL at 25°C)
Solubility in Other Solvents: Soluble in ethanol, DMSO, and acetone
Odor: Odorless

Applications
Laboratory Research:

• Used in studies on circadian rhythms, sleep-wake cycles, and photoperiodism.

• Investigated for its antioxidant and free-radical scavenging properties.

• Applied in receptor binding and neurochemical studies.

Organic Synthesis:

• Used as a starting point for the synthesis of indole-based compounds and derivatives for further biochemical studies.

Key Properties

• High Purity: >99%, suitable for accurate and reproducible laboratory research.

• Biologically Relevant: Mimics naturally occurring melatonin in mammals and plants.

• Stable: Chemically stable under standard laboratory storage conditions when protected from light.

Important Note:
This product is intended strictly for laboratory research purposes. It is not approved for human consumption or pharmaceutical use.

Safety

This chemical does not meet GHS hazard criteria for 96.5% (139 of 144) of all reports.

Handling and Storage
Storage Conditions:

• Store in a tightly closed container, in a cool, dry, and dark place.

• Recommended storage temperature: 2–8°C.

• Protect from light and moisture to prevent degradation.

Handling Precautions:

• Handle under low-light conditions if possible to prevent photodegradation.

• Use appropriate PPE when working with powdered forms.