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Opis
Quinoline
Other Names: 1-Benzopyridine, Benzo[b]pyridine, Leukol, Leucoline, Benzazine, Benzazabenzene, Benzopyridine, 1-Benzine, Quinolin
CAS Number: 91-22-5
Sum Formula: C₉H₇N
Molar Mass: 129.16 g/mol
Appearance: Colorless to pale yellow oily liquid (darkens on exposure to air and light)
Quinoline is a heterocyclic aromatic organic compound with a fused benzene and pyridine ring system. It is a basic compound and serves as a key building block in the synthesis of complex organic molecules, dyes, and materials for industrial and laboratory use.
Chemical and Physical Properties
Density: 1.09 g/cm³
Melting Point: –15°C
Boiling Point: 238°C
Solubility in Water: Slightly soluble (0.6 g/100 mL at 25°C)
Solubility in Other Solvents: Miscible with ethanol, ether, benzene, and chloroform
Odor: Strong, penetrating, unpleasant odor (similar to pyridine)
Applications
Organic Synthesis: Used as a precursor to various quinoline derivatives in chemical manufacturing.
Industrial Chemistry: Involved in the production of dyes, rubber accelerators, and corrosion inhibitors.
Coordination Chemistry: Serves as a ligand in the formation of metal complexes.
Analytical Chemistry: Sometimes used in fluorescence and spectroscopic studies.
Safety
Signal Word: Danger
H302 (91.6%): Harmful if swallowed [Warning Acute toxicity, oral]
H312 (90.1%): Harmful in contact with skin [Warning Acute toxicity, dermal]
H315 (99.8%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H341 (99.8%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]
H350 (99.8%): May cause cancer [Danger Carcinogenicity]
H411 (99.8%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
P203, P264, P264+P265, P270, P273, P280, P301+P317, P302+P352, P305+P351+P338, P317, P318, P321, P330, P332+P317, P337+P317, P362+P364, P391, P405, and P501
Handling and Storage
Storage Conditions: Store in tightly sealed containers in a cool, dry, and well-ventilated area. Protect from light, air, and incompatible materials such as strong oxidizers and acids.
Handling Precautions: Avoid contact with skin, eyes, and clothing. Use in a chemical fume hood with proper protective equipment. Handle under an inert atmosphere if prolonged storage is required.