Comfrey Oil
Other Names: Symphytum officinale oil, Comfrey root extract in oil

CAS Number: Not assigned (mixture – no single CAS)
Composition: Typically an infusion or maceration of Symphytum officinale (comfrey) root or leaf in a carrier oil such as olive oil or sunflower oil
Appearance: Yellow to greenish-brown oily liquid
Odor: Mild, herbaceous

Comfrey oil is a natural herbal extract obtained by infusing comfrey roots or leaves in a carrier oil. It contains active compounds such as allantoin, rosmarinic acid, and mucilage, and is traditionally used in topical formulations. Due to the presence of pyrrolizidine alkaloids (which are hepatotoxic when ingested), comfrey oil is used externally only.

Chemical and Physical Properties
Solubility: Insoluble in water, miscible with fats and oils
Boiling Point: Not applicable (mixture)
Density: Depends on the carrier oil, typically around 0.91–0.93 g/cm³

Applications
Topical Preparations: Used in ointments, creams, and massage oils for its purported skin-soothing and regenerative properties.
Cosmetic Formulations: Common in herbal skin care products for conditioning and moisturizing effects.
Herbal and Aromatherapy Uses: Applied externally in natural wellness practices for muscle and joint support.

Safety
Signal Word: Warning (for external use only)

Hazard Considerations:

• Not intended for ingestion due to potential hepatotoxicity of pyrrolizidine alkaloids.

• May cause allergic skin reactions in sensitive individuals.

Precautionary Statements:

• For external use only

• Avoid contact with eyes

• Do not apply to broken or irritated skin

• Keep out of reach of children

Handling and Storage
Store in a cool, dark place in a tightly closed container. Avoid exposure to heat and sunlight to preserve the oil’s integrity. Use within the recommended shelf life provided by the supplier.