N-Acetyl-L-tyrosine Powder
Other Names: (2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid

CAS Number: 537-55-3
Sum Formula: C₁₁H₁₃NO₄
Molar Mass: 223.23 g/mol
Appearance: White to off-white crystalline powder

N-Acetyl-L-tyrosine is an acetylated derivative of the amino acid L-tyrosine, where the amino group is blocked by an acetyl group. This modification improves its chemical stability and alters its solubility properties, making it valuable in synthetic, material science, and analytical applications.

Chemical and Physical Properties
Density: ~1.34 g/cm³ (estimated)
Melting Point: 300–305°C (decomposes)
Boiling Point: Not applicable (decomposes)
Solubility in Water: Sparingly soluble (~10 g/L at 25°C)
Solubility in Other Solvents: Slightly soluble in alcohol; practically insoluble in ether and chloroform
Odor: Odorless

Applications
Peptide and Protein Synthesis: Used as a protected tyrosine derivative in synthetic peptides.
Organic Synthesis: Intermediate in the preparation of biofunctionalized molecules and ligands.
Material Science: Incorporated into bioactive polymers and surface modification materials.
Analytical Chemistry: Applied in studies involving post-translational modifications and amino acid derivatization.
Coordination Chemistry: Investigated as a ligand with potential for metal complexation.

Safety

Signal Word: Warning

Handling and Storage
Storage Conditions: Store in a tightly sealed container in a cool, dry, and well-ventilated place. Protect from moisture, light, and strong oxidizing agents.
Handling Precautions: Avoid dust formation and prolonged exposure to air. Use appropriate PPE and follow standard laboratory handling procedures.