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D-Ribose
Other Names: D-(−)-Ribose, β-D-Ribofuranose
CAS Number: 50-69-1
Sum Formula: C₅H₁₀O₅
Molar Mass: 150.13 g/mol
Appearance: White crystalline powder
D-Ribose is a naturally occurring monosaccharide (simple sugar) with five carbon atoms, classified as an aldopentose. It plays a critical role in biological systems as a structural component of nucleotides and nucleic acids and supports ATP (adenosine triphosphate) production, serving as a key sugar backbone in energy metabolism and biosynthesis processes.
Chemical and Physical Properties
Density: ~1.52 g/cm³ (estimated)
Melting Point: 87–92°C
Boiling Point: Decomposes before boiling
Solubility in Water: Freely soluble
Solubility in Other Solvents: Slightly soluble in ethanol; practically insoluble in nonpolar solvents
Odor: Odorless
Applications
Biochemical Research: Used in studies of nucleotide and nucleic acid synthesis, including DNA and RNA formation.
Energy Metabolism Support: Studied for its role in promoting ATP regeneration and cellular energy pathways.
Organic Synthesis: Employed as a starting material for the preparation of nucleotide analogs and biochemical intermediates.
Material Science: Incorporated into biopolymer research for creating ribose-based materials.
Analytical Chemistry: Used as a standard and reactant in carbohydrate analysis and derivatization protocols.
Safety
This chemical does not meet GHS hazard criteria for 99.3% (152 of 153) of all reports.
Handling and Storage
Storage Conditions: Store in a tightly sealed container in a cool, dry, and well-ventilated environment. Protect from moisture and strong oxidizing agents.
Handling Precautions: Minimize dust formation and avoid contact with eyes or mucous membranes. Use appropriate personal protective equipment.
